Effect of dexmedetomidine combined with azasetron on nausea and vomiting after thyroidectomy: a randomized controlled trial.

Effect of dexmedetomidine combined with azasetron on nausea and vomiting after thyroidectomy

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000039603

Enrollment

Unknown

Registered

2020-11-03

Start date

2020-11-02

Completion date

Unknown

Last updated

2021-02-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative nausea and vomiting

Interventions

dexmedetomidine+azasetron group:Dexmedetomidine +azasetron was used intraoperatively

azasetron group: azasetron was used intraoperatively

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients scheduled for thyroidectomy; 2. ASA I-II objects; 3. Subjects aged 18-60 years old; 4. 18 <= BMI <= 24.

Exclusion criteria

Exclusion criteria: 1. Patients with history of severe hypertension; 2. Subjects with significant abnormal liver and kidney functions; 3. Subjects with significant abnormal coagulation function; 4. The subjects who took opioids for a long time before operation; 5. The subject of sedation and analgesia; 6. The target of psychotropic drugs; 7. The subject suffering from mental illness or unable to correctly express the will.

Design outcomes

Primary

Measure	Time frame
Incidence of postoperative nausea and vomiting;	—

Secondary

Measure	Time frame
Visual Analogue Scale pain score;Ramsay sedation score;	—

Countries

China

Contacts

Public ContactLu Yao

Department of Anesthesiology, the First Affiliated Hospital of Anhui Medical University

luyao-mz@163.com+86 18956564060

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026