Obese Diabetes
Conditions
Interventions
Surgical group:Sleeve gastreetomy
Control group: routine hypoglycemic treatment
Sponsors
Changzhou No. 2 People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Diagnostic criteria for diabetes mellitus were specified in accordance with the American Diabetes Association (ADA, 1997); 2.body mass index (BMI) >= 28 kg/m2; 3.Age: 18-65 years; 4.The course of diabetes = 1/2 of the lower limit of normal value; 5.Surgical group: patients come to our hospital to prepare for gastric sleeve resection;Control group: patients came to our hospital for routine hypoglycemic treatment, not prepared for gastric cuff resection. 5.Preparation for sleeve gastrectomy.
Exclusion criteria
Exclusion criteria: 1.Diagnosis of type 1 diabetes; 2.Patients with gestational diabetes and certain specific types of diabetes; 3.Drug or alcohol abusemental illness with difficult control 4.Mental retardation or intellectual immaturity, behavior can not be self-control; 5.Poor general condition, difficult to tolerate general anesthesia or surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| insulin sensitivity index; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood glucose;Total cholesterol;Triglyceride;Low-density lipoprotein cholesterol;High density lipoprotein cholesterol;glutamic-pyruvic transaminase;serum creatinine;insulin;serum C-peptide;glycated hemoglobin;Glucagon-like peptide 1;Ghrelin;Bile acid;free fatty acid;tumor necrosis factor-a;Interleukin-6;leptin;adiponectin;Liver fat content; | — |
Countries
China
Contacts
Public ContactShi Li
Department of Endocrinology, Changzhou No. 2 People's Hospital
Outcome results
None listed