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Exploration on the mechanism of modern Chinese Medication fasting reversing /improving metabolic endotoxemia in type 2 diabetes mellitus based on gut microbiota metagenomics sequencing

Exploration on the mechanism of modern Chinese Medication fasting reversing /improving metabolic endotoxemia in type 2 diabetes mellitus based on gut microbiota metagenomics sequencing

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000039597
Enrollment
Unknown
Registered
2020-11-02
Start date
2019-06-01
Completion date
Unknown
Last updated
2021-02-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 2 diabetes mellitus

Interventions

modern Chinese Medication fasting:modern Chinese Medication fasting

Sponsors

The Seventh Affiliated Hospital, Sun Yat-Sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 52 Years

Inclusion criteria

Inclusion criteria: 1. Aged 25-65 years; 2. Newly diagnosed type 2 diabetes (diagnostic criteria refer to "Chinese Type 2 Diabetes Prevention Guidelines (2017 Edition)"); 3. Overweight/obesity: BMI >= 24kg/m2; 4. Heart Liver and kidney functions are normal; 5. Comply with the "Declaration of Helsinki" and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. People who have used insulin therapy; 2. Recent glycosylated hemoglobin >= 12%; 3. Pregnant or lactating women; 4. Past Or current intestinal disease; 5. History of gastrointestinal surgery; 6. Use antibiotics for more than 3 days in the past 3 months; 7. Malignant tumor or blood disease; 8. Mental disease; 9. Severe gastric bleeding ulcer; 10. Excessive Weight loss and malnutrition; 11. Combined with serious complications; 12. 3 months using drugs or surgery to reduce weight; 13. Unable to cooperate with treatment and poor compliance; 14. The investigator judged that it is not suitable for inclusion other circumstances.

Design outcomes

Primary

MeasureTime frame
Metagenomic sequencing of intestinal flora;Metabolomics;

Countries

China

Contacts

Public ContactJian Qin

The Seventh Affiliated Hospital, Sun Yat-Sen University

himybox@yeah.net+86 18902233983

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026