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Early efficacy of autologous bone stem cell versus tricalcium phosphate grafting in the treatment of avascular necrosis of the femoral head: a prospective, randomized and controlled study

Early efficacy of autologous bone stem cell versus tricalcium phosphate grafting in the treatment of avascular necrosis of the femoral head: a prospective, randomized and controlled study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000039595
Enrollment
Unknown
Registered
2020-11-02
Start date
2015-06-01
Completion date
Unknown
Last updated
2021-02-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Avascular necrosis of the femoral head

Interventions

experimental group :autologous bone plus tricalcium phosphate transplantation
control group:tricalcium phosphate transplantation alone

Sponsors

Guangdong Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Patients aged from 18 to 60 years; 2.Patients who clearly diagnosed with avascular necrosis of femoral head, unilateral or bilateral.

Exclusion criteria

Exclusion criteria: 1. Patients who had terminal stage of avascular necrosis of femoral head with the presence of secondary osteoarthritic changes such as osteophyte hyperplasia and joint space narrowing; 2. Patients who had vascular disorders affecting lower limb function; 3. Patients who had history of lower limb fractures, bone tumors and other lesions; 4. Patients who had inflammatory arthritis such as rheumatoid arthritis, suppurative arthritis and gouty arthritis; 5. Patients who had infection in surgical site; 6. Patients who had congenital deformity or insufficiency of lower limb; 7. Patients who had undergone lower limb surgery in the past three months; 8. Patients unwilling to undergo core decompression.

Design outcomes

Primary

MeasureTime frame
Harris score;

Secondary

MeasureTime frame
Survival time of femoral head;Ficat stage of the avascular necrosis of the femoral head;Aetiology of the avascular necrosis of the femoral head;Harris Score;Harris Score;Harris Score;

Countries

China

Contacts

Public ContactQingtian Li

Center of Orthopedics Surgery, Guangdong Provincial People's Hospital

398619503@qq.com+86 18820109789

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 22, 2026