Regulating effect of alginate on intestinal microbial
Conditions
Interventions
experimental group:Sodium Alginate 10g
control group:placebo
Sponsors
Institute of Nutrition and Health, Chinese Center for Disease Control and Prevention
Eligibility
Sex/Gender
Male
Age
18 Years to 25 Years
Inclusion criteria
Inclusion criteria: Males between the ages of 18 and 25 years who have maintained a stable body weight for at least six months, have normal fasting blood glucose, lipid, liver and kidney function, eat a regular diet, have no functional constipation or diarrhea, and can tolerate a 12-hour nocturnal fasting state the day before each trial.
Exclusion criteria
Exclusion criteria: Participants whose parents have diabetes, are currently taking certain medications or undergoing certain treatments, are allergic to one or more foods, have a particular diet (high-protein diet, vegetarian, etc.), and are going to participate in another trial within the last month. Those who have taken antibiotics in the last 2 months, those who have a habit of regularly consuming fermented products such as yogurt are to be considered for exclusion or discontinuation of yogurt 10-15 days prior to enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 16S DRNA gene sequencing of gut microbes; | — |
Secondary
| Measure | Time frame |
|---|---|
| Glycemic index; | — |
Countries
China
Contacts
Public ContactQingbin Xing
Peking University
Outcome results
None listed