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The study of clinical application of Ultrasound-guided thermal ablation for thyroid lesion

The study of clinical application of Ultrasound-guided thermal ablation for thyroid lesion

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000039563
Enrollment
Unknown
Registered
2020-10-31
Start date
2020-11-01
Completion date
Unknown
Last updated
2021-02-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

thyroid disease

Interventions

Benign group vs. Malignant group:Nil

Sponsors

People's Liberation Army General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Benign group: 1. Cytologically confirmed benign nodules A, Ti-RADS type 2-3 (according to classification system); 2. Subjective symptoms, such as neck discomfort or pain, pressure, foreign body sensation; 3. Affect the appearance; 4. Not suitable or refused to operate; 5. Fear of developing into malign. Malignant group: 1. Patients with malignant tumor confirmed by pathology (CNB); 2. Receive RFA treatment; 3. No external thyroid invasion, lymph node metastasis or distant metastasis were detected by ultrasound; 4. Follow-up time was longer than 6 months; 5. Unable or refused surgery

Exclusion criteria

Exclusion criteria: Benign group: 1. Puncture proved to be malignant; 2. The ultrasound showed malignant signs (aspect ratio > 1, microcalcification, very low echo, unclear boundary), although the puncture results were benign. Malignant group: 1. Multiple malignant tumors; 2. Metastatic carcinoma; 3. Severe coagulation disorders, respiratory failure, myocardial infarction, systemic infection, or uncontrolled diabetes; 4. Neuropsychiatric disorders or neck extension disorders that lead to RFA intolerance; 5. Pacemaker implantation; 6. Contralateral vocal cord paralysis; 7. Allergic to sulfur hexafluoride microbubbles; 8. Incomplete case data.

Design outcomes

Primary

MeasureTime frame
TSH;The volume of exudate;

Countries

China

Contacts

Public ContactLuo Yukun

The First Medical Center of PLA General Hospital

dingdanglanyu@126.com+86 13311373556

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026