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Study on the dose-effect relationship of dexmedetomidine combined with low-concentration local anesthetics for labor analgesia

Study on the dose-effect relationship of dexmedetomidine combined with low-concentration local anesthetics for labor analgesia

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000039547
Enrollment
Unknown
Registered
2020-10-31
Start date
2020-11-05
Completion date
Unknown
Last updated
2021-02-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Labor analgesia

Interventions

control group:ropivacaine alone
Sufentanil group:Sufentanil + ropivacaine
Dexmedetomidine group:Dexmedetomidine + ropivacaine
Normal BMI group:Dexmedetomidine + ropivacaine
Overweight BMI group:Dexmedetomidine + ropivacaine

Sponsors

Chongqing Health Center for Women and Children
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Primiparous, singleton head position and full-term pregnancy; 2. Vaginal delivery, with normal communication skills, able to understand the content of the informed consent form and independently think and make judgments; 3. ASA level II, no preeclampsia, gestational diabetes, pregnancy Pregnancy complications such as intrahepatic cholestasis; 4. No history of anesthetic drug allergy, voluntary epidural analgesia without systemic analgesia; 5. Agreed to participate in this study and signed an informed consent.

Exclusion criteria

Exclusion criteria: 1. There is mental illness and cognitive dysfunction; 2. Maternal intraspinal analgesia risk; 3. Absolute and relative contraindications of intraspinal anesthesia; 4. Parturients transferred to cesarean section.

Design outcomes

Primary

MeasureTime frame
Hemodynamic;VAS score;Duration of labor;

Secondary

MeasureTime frame
Apgar score;Cord blood gas analysis;Parturient women satisfaction;

Countries

China

Contacts

Public ContactYu Jin

Chongqing Health Center for Women and Children

dodoes@qq.com+86 18623117820

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026