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EGFR regulates macrophage polarization by phosphorylating Rab7A-mediated metabolic reprogramming Study on the role and molecular mechanism of sepsis

EGFR regulates macrophage polarization by phosphorylating Rab7A-mediated metabolic reprogramming Study on the role and molecular mechanism of sepsis

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000039545
Enrollment
Unknown
Registered
2020-10-31
Start date
2020-11-10
Completion date
Unknown
Last updated
2021-02-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

Group of patients with sepsis:Collect blood from patients with sepsis

Sponsors

Affiliated Hospital of Guangdong Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients or family members give informed consent to the study and sign the informed consent; 2. Hospitalized patients with sepsis; 3. No male or female, age 18 or above; 4. Patients without other serious systemic diseases.

Exclusion criteria

Exclusion criteria: 1. Accompanied by severe heart, liver, kidney and hematopoietic diseases; 2. Patients with complicated malignant tumor; 3. He had a central nervous system and mental illness before surgery.

Design outcomes

Primary

MeasureTime frame
epidermal growth factor;

Countries

China

Contacts

Public ContactTang Jing

Affiliated Hospital of Guangdong Medical University

tanglitangjing@126.com+86 13189091282

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026