Severe Acute Pancreatitis
Conditions
Interventions
Medical therapy:Nil
Blood purification:Nil
Sponsors
Center of Severe Acute Pancreatitis,Department of Critical Care Medicine, Jinling Hospital, Medical School of Nanjing University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18 to 70 years; 2. Within 72 hours of onset, With a primary diagnosis of HTG-AP; 3. When enrolled, TG>1000mg/dL (11.3mmol/L), accompanied by the clinical worrisome features of any one or more of the following: 1) Signs of hypocalcaemia (calcium levels less than 2.1mmol/L); 2) Lactic acidosis (Lactate levels more than 2mmol/L and PH 38.5 degrees C or 90 /min; Respiratory rate of >20 breaths/min or PaCO2 of 12,000 cells/mL, 10 percent immature (band) forms; 4) Signs of worsening organ dysfunction or multi-organ failure as defined by Modified Marshall scoring system for organ dysfunction.
Exclusion criteria
Exclusion criteria: 1. Without informed consent; 2. Pregnant or lactating women; or have a pregnancy plan within 1 month after the test (including male subjects); 3. Researchers family members who are directly involved in the trial; 4. Patients are expected to die within 48 hours after enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Organ failure free day; | — |
Countries
China
Contacts
Public ContactZhihui Tong
Center of Severe Acute Pancreatitis, Department of Critical Care Medicine, Jinling Hospital, Medical School of Nanjing University
Outcome results
None listed