lung cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: To be enrolled in this study, participants must meet all the following inclusion criteria: 1.Aged 18-80 years, male or female not limited; 2.Pathological diagnosis of non-small cell lung cancer; 3.Subjects not suitable for or refusing surgical and radiotherapy; 4.Subjects who are able to tolerate anesthesia (local or general/epidural as required) and have a puncture route; 5.There were clinical lesions that could be evaluated, with a maximum diameter of 5cm; 6.Except for the lesion to be ablated, the other lesions were stable; 9.The main organs function well and meet the following criteria: (1) Blood routine examination a)Hb >= 90g/L;b) Platelet count of >= 100*10^9/L; c) Absolute neutrophil count >= 1.5*10^9/L; (2) Blood biochemistry a) Total bilirubin = 80% of the expected value, and without significant ventilation dysfunction; 10. Women of childbearing age should exclude pregnancy. 11. Voluntary participation and informed consent. 12. Compliance is good, agree to cooperate with follow-up.
Exclusion criteria
Exclusion criteria: Participants who meet any of the following criteria will not be enrolled in this study: 1. The target lesion is close to the major vessels, bronchus, pleura or other important organs (within 1cm). 2. Pregnant or lactating women or subjects of childbearing age who plan to pregnance. 3. Severe heart, lung, liver and renal insufficiency. 4. Blood routine examination: absolute neutrophil count < 1.5*109/L or platelet count < 100 * 10^9/L. 5. Subjects with acute or chronic infection. 6. Abnormal thyroid function. 7. Mental disorders or a history of mental illness. 8. Whthin 3 months of participation in other clinical investigators. 9. People with coagulation disorders. 10. The researchers determined that microwave ablation is not suitable.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy (Angle and depth of ablation needle); | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety (perioperative complications); | — |
Countries
China
Contacts
Department of Radiation Oncology, Peking University Third Hospital