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Application of tranexamic acid in knee arthroscopy: a randomized controlled trial

Application of tranexamic acid in knee arthroscopy: a randomized controlled trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000039528
Enrollment
Unknown
Registered
2020-10-30
Start date
2020-11-01
Completion date
Unknown
Last updated
2021-02-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Meniscus and cruciate ligament injury

Interventions

group A:TXA+Placebo+Placebo
group B:Placebo+TXA+Placebo
group C:Placebo+Placebo+TXA
group D:Placebo+Placebo+Placebo

Sponsors

The Third People's Hospital of Mianyang
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients who are to undergo arthroscopic knee surgery for unilateral knee joint disorders (meniscus or cruciate ligament injuries). 2. Aged >= 18 years. 3. All patients had informed consent, signed the informed consent of surgery and the agreement of participating in clinical research.

Exclusion criteria

Exclusion criteria: 1. Knee arthroscopy for arthropathy of both knees. 2. Knee cruciate ligaments and meniscus without damage, only underwent debridement; 3. Allergy to tranexamic acid or had contraindications; 4. Patients receiving anticoagulant therapy such as warfarin or clopidogrel; 5. high risk of thrombosis or history of thromboembolism (within half a year).

Design outcomes

Primary

MeasureTime frame
Circumference of knee joint;Visual Analogue Scale;Knee Function Score;

Secondary

MeasureTime frame
Hemoglobin level and decline;Total blood loss;Knee range of motion;use of analgesics;

Countries

China

Contacts

Public ContactCong Xiao

The Third People's Hospital of Mianyang

xiaocong889900@163.com+86 13890459183

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026