chronic obstructive pulmonary disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Those who meet the diagnostic criteria in the guidelines for the diagnosis and treatment of chronic obstructive pulmonary disease (2007 revised edition), and FEV1.0/FVC<70% and FEV1.0pre<80% after using bronchodilator; 2.Aged 40-85 years; 3.Signing informed consent and undertaking to complete the relevant assessment according to the experimental requirements;
Exclusion criteria
Exclusion criteria: 1. Patients with various neuromuscular and joint diseases that affect swallowing function; those with cognitive impairment who can not cooperate with the assessment; 2. patients with various severe cardiovascular and respiratory diseases that affect cardiopulmonary motor function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the time of swallow apnoea;SEN, SPE, ACC, AUC of ROC; | — |
Secondary
| Measure | Time frame |
|---|---|
| lung function test;St George's Respiratory Questionnaire;the Frequency Scale for the Symptoms of GORD;Blood Routine Indexes;cardiopulmonary exercise testing;diaphragm excusion;diaphragm thicking;WHO DAS 2.0;6-minutes walk testing;walk speed;body composition analysis; | — |
Countries
China
Contacts
Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences