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Effect of high frequency repetitive transcranial magnetic stimulation combined with wrist ankle acupuncture on spastic state and motor function in children with spastic cerebral palsy

Effect of high frequency repetitive transcranial magnetic stimulation combined with wrist ankle acupuncture on spastic state and motor function in children with spastic cerebral palsy

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000039495
Enrollment
Unknown
Registered
2020-10-30
Start date
2020-08-01
Completion date
Unknown
Last updated
2021-02-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebral palsy

Interventions

Experimental group:High frequency repetitive transcranial magnetic stimulation and wrist ankle acupuncture
control group:High frequency repetitive transcranial magnetic stimulation

Sponsors

Shanghai University of traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 7 Years

Inclusion criteria

Inclusion criteria: 1. Children with spastic cerebral palsy who met the diagnostic criteria of cerebral palsy, mainly manifested as hyperactivity of stretch reflex; 2. Aged from 3 to 7 years old, with GMFCS grade I-II; 3. Without coagulation dysfunction; 4. With the consent of the child's guardian and voluntary signing of informed consent.

Exclusion criteria

Exclusion criteria: 1. The patients who could not induce bilateral cortical motor evoked potential by single pulse transcranial magnetic stimulation and neurological function diagnostic instrument; 2. MRI showed intracranial space occupying lesions and hydrocephalus in children; 3. Children with heart, liver and kidney insufficiency, history of epilepsy, severe cognitive impairment or other serious diseases; 4. Children with involuntary movement or mixed cerebral palsy; 5. Patients with cardiac pacemaker, cochlear implant, intracranial vascular stent, metal internal fixation and other implants; 6. In recent one month, the patient took or injected anti spasmodic and other related drugs.

Design outcomes

Primary

MeasureTime frame
Gross Motor Function Measure-66;the Peabody Developmental Motor Scales-Second Edition;Modified Tardieu Scale;

Secondary

MeasureTime frame
Latency and amplitude of motor evoked potential;motor threshold;central motor conduction time;central motor conduction tim;

Countries

China

Contacts

Public ContactLi Jiamin

Shanghai University of traditional Chinese Medicine

851055428@qq.com+86 13917245215

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026