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Coptis Chinensis-Scutellaria for primary hypertension of heart-and-liver fire syndrome: a randomized, double-blind controlled trial

The mechanism of Coptis Chinensis - Scutellaria for primary hypertension of heart-and-liver fire syndrome through the gut - sympathetic nervous system axis

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000039488
Enrollment
Unknown
Registered
2020-10-30
Start date
2020-10-20
Completion date
Unknown
Last updated
2021-02-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Hypertension

Interventions

Sponsors

Beijing Chao-Yang Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosed with primary hypertension, having mean systolic blood pressure >= 140 mmHg and = 90mmHg and < 110 mmHg without antihypertensive therapy; 2. Diagnosed of heart-and-liver fire syndrome; 3. Aged between 18-65 years, both male and female; 4. Signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Definite or suspected secondary hypertension; 2. Usingßblockers; 3. Endocrine diseases such as diabetes and thyroid disease; 4. Unstable angina,myocardial infarction,heart failure disease or cerebrovascular accident; 5. Combined with some other cardiovascular, cerebrovascular, liver, kidney, hematopoietic system and other serious primary diseases or malignancy (include unilateral or bilateral renal artery stenosis); 6. Chronic gastrointestinal disorders; 7. Diarrhea or other gastrointestinal diseases in the past month,or taking microecological preparations, hormone drugs or antibiotics within the past month; 8. Allergic constitution or allergic to multiple drugs; 9. Pregnancy or lactation women or recent pregnancy preparation.

Design outcomes

Primary

MeasureTime frame
SeDBP;SeSBP;Rate of BP;Hypertension symptom score;Headache symptom score;ABPM;TCM symptom score;PSQI;

Countries

China

Contacts

Public ContactDong Zhenyu

Beijing Chaoyang Hospital, Capital Medical University

dzy1010@163.com+86 10-85231046

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026