Prospective clinical study on dynamic evolution of increased signal intensity (ISI) on T2-Weighted MRI in patients with degenerative cervical myelopathy

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000039469

Enrollment

Unknown

Registered

2020-10-28

Start date

2021-01-01

Completion date

Unknown

Last updated

2021-02-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Degenerative cervical myelopathy

Interventions

Group 1:Grade 0 of ISI

Group 2:Grade 1 of ISI

Group 3:Grade 2 of ISI

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients with the diagnosis of degenerative cervical myelopathy; 2.Patients with no history of cervical trauma or spinal surgery; 3.Patients with complete radiological data, including preoperative and postoperative cervical X-ray film, CT and MRI; 4.Patients who comply with the classification of increased signal intensity on T2-Weighted MRI.

Exclusion criteria

Exclusion criteria: 1.Patients with severe primary diseases such as liver, kidney, hematopoietic system, endocrine system and psychosis; 2.Patients with cervical kyphosis > 13 degrees; 3.Patients with ankylosing spondylitis or rheumatoid arthritis; 4.Patients with neuromuscular diseases, infections and tumors.

Design outcomes

Primary

Measure	Time frame
Japanese Orthopaedic Association Scores (JOA);Nurick grade;Visual Analogue Score (VAS);Neck Disabilitv Index (NDI);The MOS item short from health survey (SF-36);	—

Countries

China

Contacts

Public ContactCao Peng

Shanghai Changzheng Hospital

mdpinocao@163.com+86 18610096198

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026