breast cancer
Conditions
Interventions
Tgroup:Ultrasound-guided thoracic paravertebral block
Sgroup:Pseudothoracic paravertebral block
Sponsors
Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
Female
Age
30 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Aged 30-55 years; 2. ASA grade I ~ II; 3. Body Mass Index (BMI) 18-30 kg/m2; 4. TNM stage: T1-3N0-3m0; 5. Unilateral elective radical mastectomy is proposed; 6. Agreed to participate in the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with contraindication of thoracic paravertebral blockade: abnormal coagulation function, puncture site infection, local anesthetic allergy, etc.; 2. Previous breast cancer surgery (excluding needle aspiration cytology biopsy) or a history of chronic pain; 3. Inflammatory breast cancer; He/she has a history of other cancers or other tumor surgery; 4. Antihistamine or analgesic or sedative drugs were used 24 h before operation; 5. Long-term history of opioid or antiemetic use; 6. Cannot cooperate with researchers for any reason: hearing or vision impairment, language comprehension impairment, mental illness, etc.; 7. Preoperative blood routine shows obvious abnormal lymphocyte or with other damage to the immune system diseases (such as: leukemia, autoimmune disease, immunodeficiency disease, etc.) or long-term use of immunosuppressive patients; 8. Men and pregnant women; 9. Pet-x is associated with central neuropathy, hepatic and renal dysfunction and hypotension (systolic pressure <= 90 mmHg). 10. The corpse has joined other researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative first rescue analgesia time;Postoperative NLR count; | — |
Countries
China
Contacts
Public ContactMing Xia
Outcome results
None listed