depression
Conditions
Interventions
PAS10:PAS10
PAS25:PAS25
Sponsors
Guangdong Provincial Hospital of Tradition Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: (1) Aged range 18-50 years, male or female, right handed; (2) Heathy group: Healthy in the past, denied hepatitis, tuberculosis, hypertension, diabetes, heart disease etc. The score of Hamilton Depression Scale (HAMD-24) is less than 8, which is not in accordance with the diagnosis criteria of depressive disorder according to Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5); (3) Depression group: Met DSM-5; HAMD-24 score is over 8; (4) No medical treatment, physical and psychological therapy more than 3 weeks or maintain stable medical treatment at least 3 weeks; (5) People who volunteer to participate in this study and sign the written informed consent.
Exclusion criteria
Exclusion criteria: (1) History of self harm or suicide; (2) History of schizophrenia, bipolar disorder or severe personality disorder; (3) History of alcohol abuse or drug dependence; (4) History of severe traumatic brain injury or epilepsy; (5) Participants who have serious cardiovascular diseases, liver diseases or kidney diseases; (6) People who refuse acupuncture treatment during the trial; (7) Metal implant in skull or pacemaker; (8) Women in pregnant or lactating.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Motor evoked potentials (MEPs); | — |
Secondary
| Measure | Time frame |
|---|---|
| The resting motor threshold (rMT);Contralateral silent period (CSP);Trail making testAB;Rey Auditory Verbal Learning Test (RAVLT); | — |
Countries
China
Contacts
Public ContactJianhua Liu
Guangdong Provincial Hospital of Tradition Chinese Medicine
Outcome results
None listed