Effect of dexmedetomidine combined with dexamethasone on nausea and vomiting after laparoscopic cholecystectomy

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000039407

Enrollment

Unknown

Registered

2020-10-26

Start date

2020-11-01

Completion date

Unknown

Last updated

2021-02-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative nausea and vomiting

Interventions

dexamethasone group:dexamethasone was used intraoperatively

dexmedetomidine+dexamethasone group:Dexmedetomidine+ dexamethasone was used intraoperatively

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients scheduled for laparoscopic cholecystectomy; 2. Patients with ASA grade I-II; 3. Patients aged 18-60 years old; 4. 18 <= BMI <= 24.

Exclusion criteria

Exclusion criteria: 1. Patients with history of severe hypertension; 2. Subjects with significant abnormal liver and kidney functions; 3. Subjects with significant abnormal coagulation function; 4. Patients taking opioids, sedative and analgesic drugs and psychotropic drugs for a long time before operation; 5. Patients with mental illness or unable to express their wishes correctly.

Design outcomes

Primary

Measure	Time frame
The incidence of nausea and vomiting within 24 hours after surgery;	—

Secondary

Measure	Time frame
Visual analog pain score;Ramsay sedation scale;	—

Countries

China

Contacts

Public ContactLu Yao

Department of Anesthesiology, the First Affiliated Hospital of Anhui Medical University

luyao-mz@163.com+86 18956564060

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026