Senile laparoscope
Conditions
Interventions
Control group :Propofol 4mg/kg/h
The research group A:Remazolam toluenesulfonic acid 1mg/kg/h
The research group B:Remazolam toluenesulfonic acid 2mg/kg/h
The research group C:Remazolam toluenesulfonic acid 3mg/kg/h
Sponsors
Tangshan Central Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 75 Years
Inclusion criteria
Inclusion criteria: Laparoscopic surgery patients with ASA II - III level; Ages 60-75 years, regardless of gender; The operation lasts 2-3 hours.
Exclusion criteria
Exclusion criteria: 1. Those with incomplete clinical examination data and researchers think it is inappropriate to participate in this study. 2. MAP < 50mmHg and heart rate (H R) < 60 times /min were excluded for severe cardiopulmonary function, coagulation dysfunction, hemodynamic instability and other diseases. 3. Hypertensive patients whose blood pressure is not satisfactorily controlled by antihypertensive drugs; 4. Patients with water and electrolyte disturbances, severe atrioventricular block and severe cardiac insufficiency; 5. Patients with drug intolerance or allergy are known in this study; 6. Patients with peripheral vascular diseases, recent use of vasoactive drugs, antidepressants and painkillers; 7. Have a history of brain injury, intracranial hypertension, cerebral aneurysm, cerebrovascular accident and central nervous system disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean arterial pressure, heart rate, blood oxygen saturation, and BIS;Induction duration and intubation time;Postoperative eye opening time, consciousness recovery time, PACU residence time and directional force recovery time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Occurrence of intraoperative and postoperative adverse reactions; | — |
Countries
China
Contacts
Public ContactYanrong Xu
Department of Anesthesiology, Tangshan Central Hospital
Outcome results
None listed