thoracoscopic partial lung resection
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Elective thoracoscopic partial lung resection in the second Xiangya Hospital requiring general anesthesia; 2. Aged 18 to 75 years; 3. Written informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients undergoing nerve block during perioperative period; 2. Patients with abnormal white blood cells in preoperative blood routine examination tested in the ward; 3. Patients undergoing reoperation for lung cancer; 4. Patients with autoimmune diseases; 5. Patients with severe abnormal liver and kidney functions; 6. Patients with a recent history of non-steroidal anti-inflammatory drugs or steroids; 7. Patients with a history of drug or narcotics dependence; 8. Patients with a history of mental disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| percentage of white blood cell subsets;expression of proBDNF;concentration of BDNF; | — |
Secondary
| Measure | Time frame |
|---|---|
| expression of IL-1ß;expression of IL-6;expression of IL-8;expression of IL-10;expression of IL-17;expression of TNF-a;proliferation of white blood cell subsets;apoptosis of white blood cell subsets;ROS content;blood pressure;heart rate;procalcitonin;erythrocyte seedimentation rate;C-reactive protein;adrenocorticotropic hormon;cortisol;adrenalin;noradrenaline;liver function;kidney function;blood glucose;lactate;myocardial enzyme;NT-proBNP;D - dimer;endotoxin quantification;pain score;analgesic usage;length of surgery;pathological examination results;complications;ventilation time;tracheal extubation time;length of stay;expression of p75NTR;ICU length of stay; | — |
Countries
China
Contacts
Department of Anesthesia, the Second Xiangya Hospital of Central South University