Diabetic Foot
Conditions
Interventions
Sponsors
Longhua Hospital Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Those who meet the diagnostic criteria for diabetic foot disease infection; 2. Wagner classification II~IV; 3. Those who meet the diagnostic criteria of gangrene damp-heat-toxin-excessive syndrome; 4. Age between 18 and 80 years old, regardless of gender; 5. Informed consent, signed informed consent form, and voluntarily take the test.
Exclusion criteria
Exclusion criteria: 1. Combined with severe primary diseases such as cardiovascular, cerebrovascular, liver, kidney and hematopoietic system: such as blood creatinine>1.5 times the upper limit of normal, ALT > 1.5 times the upper limit of normal, proteinuria >+ (>30mg/dl) , Arrhythmia with clinical significance; 2. Severe infections, multiple system dysfunction or failure, and septic shock; 3. Pregnant or lactating women; 4. Patients with allergies; 5. Mental patients; 6. Malignant tumors or AIDS patients; 7. According to the researcher's judgment, other personal history that reduces the possibility of enrollment or complicates enrollment, such as frequent changes in the work environment, may easily cause loss to follow-up; 8. Subjects who are participating in clinical studies of other drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| amputation rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| TCM syndrome score;wound area;blood routine;C reactive protein;procalcitonin;erythrocyte sedimentation rate;tumor necrosis factor alpha;Interleukin 2;Interleukin 4;Interleukin 6;Interleukin 10; | — |
Countries
China
Contacts
Public ContactHuafa Que
Longhua Hospital Shanghai University of Traditional Chinese Medicine
Outcome results
None listed