Recurrent miscarriages and failed repeated implantation
Conditions
Interventions
Sponsors
Shenzhen Maternity and Child Healthcare Hospital
Eligibility
Sex/Gender
Female
Age
28 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Aged < 40 years; 2. Subjects with regular menstruation (28-40 days); 3. Subjects with normal basal endocrine level (FSH < 10iu / L, LH < 10iu / L, E2 < 50pg / ml); 4. Subjects of repeated abortion and repeated planting failure.
Exclusion criteria
Exclusion criteria: 1. Patients with suspected pelvic infection or recent history of pelvic infection (within 4 weeks); 2. Clinical investigation showed one or more of the following positive results: abnormal chromosome analysis of parents, abnormal immune indexes such as anticardiolipin antibody and lupus anticoagulant, abnormal endocrine indexes such as thyroid function, and abnormal ultrasound examination; 3. Patients with endometriosis, adenomyosis, uterine malformation, intrauterine adhesions, submucous myoma, uterine polyps and other abnormal uterine changes detected by endoscopy; 4. Patients with systemic diseases that may cause abnormal fertility, such as diabetes or systemic lupus erythematosus, etc; 5. Patients with previous hyperprolactinemia (hPRL), history of hypothalamic and pituitary diseases, abnormal morphology or function of adrenal cortex and thyroid, and previous tumor; 6. Women with IUD; 7. Patients who had taken immunomodulatory drugs, hormonal drugs and cytotoxic drugs 3 months before treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| endometrial receptivity;rate of pregnancy;SEN, SPE, ACC, AUC of ROC; | — |
Countries
China
Contacts
Public ContactLiu Qingzhi
Shenzhen Maternal and Child Health Hospital
Outcome results
None listed