Mood disorders
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who met the diagnostic criteria of depressive episode in DSM-IV of American Psychiatric Association; 2. Patients with HAMD-17 score > 15; 3. Patients aged 18-60 years; 4. Culture: graduated from primary school or above; long term residence in Chengdu and surrounding areas; 5. Race: Han nationality; 6. Patients who voluntarily participated in this study and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with severe physical diseases and nervous system diseases; 2. Patients with eye diseases such as cataract, macular degeneration, glaucoma, retinitis pigmentosa, or diseases affecting the retina (retinopathy, diabetes, herpes, etc.); 3. Those who use psychoactive substances for a long time or in the near future; caffeine intake more than 300 mg / day; Shift workers; 4. Patients with schizophrenia, schizophrenic affective disorder, organic mental disorder, substance related mental disorder or diagnosed with other mental disorders, as well as other cognitive disorders such as mental retardation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Depression Scale;Therapeutic side effects scale; | — |
Countries
China
Contacts
Mental Health Center, West China Hospital, Sichuan University