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Construction of predictive model of heart failure in patients with atrial fibrillation and screening and verification of lncRNAs

Construction of predictive model of heart failure in patients with atrial fibrillation and screening and verification of lncRNAs

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000039349
Enrollment
Unknown
Registered
2020-10-24
Start date
2020-10-22
Completion date
Unknown
Last updated
2021-01-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart failure, atrial fibrillation

Interventions

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Sponsors

Jinshan Hospital Affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Simple atrial fibrillation without heart failure (AF+non-HF), heart failure after atrial fibrillation (AF+HF). First, volunteer to participate and sign an informed consent form. Clinical symptoms: dyspnea, fatigue, edema of lower extremities, anorexia, oliguria, or even anuria, etc. during rest or exercise, among which labor-induced shortness of breath and edema are typical clinical manifestations; Auxiliary examination: ECG, manifestations For myocardial ischemia, conduction block, and ventricular hypertrophy; chest radiograph, showing pulmonary congestion and enlarged heart shadow; cardiac color Doppler ultrasound can understand the size of ventricular cavity, valve structure; at the same time, improve the radionuclide scan or venous pressure measurement, electrolyte, kidney Function, serum natriuretic peptide concentration. Comprehensive diagnosis of heart failure based on symptoms, signs and auxiliary examination results.

Exclusion criteria

Exclusion criteria: Exclude patients with heart failure caused by hyperthyroidism, valvular heart disease, primary cardiomyopathy, heart failure, and other non-atrial fibrillation.

Design outcomes

Primary

MeasureTime frame
Readmission and death;SEN, SPE, ACC, AUC of ROC, PPV, NPV;

Secondary

MeasureTime frame
LVEF;BNP;lncRNAs;

Countries

China

Contacts

Public ContactFei Peng

Jinshan Hospital Affiliated to Fudan University

827580343@qq.com+86 18930815532

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026