Lung cancer
Conditions
Interventions
experimental group:Esketamine 0.5mg/kg was injected intravenously 5 minutes before 5min cutting
control group:Nil
Sponsors
Department of Anesthesiology, Shandong Provincial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Age 18-80 years old; ASA I-III Patients undergoing elective thoracoscopic lobectomy.
Exclusion criteria
Exclusion criteria: (1) Refusing to participate in this research; (2) Emergency operation; (3) Open operation; (4) Neurological, cognitive or mental diseases, including stroke, dementia, and schizophrenia with language disorders, or any disease that makes a meaningful postoperative visit impossible; (5) Cardiovascular disease: defined as low-output heart failure with preoperative left ventricular ejection fraction < 30%, active coronary artery disease, severe valvular heart disease with shortness of breath, symptomatic arrhythmia, pacemaker arrhythmia or AICD placement; (6) Complicated with severe lung, liver and kidney dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NRS pain score at 2 hours, 6 hours, 12 hours, 24 hours and 48 hours after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of PONV within 48 hours after operation;Ramsay sedation score;Dosage and number of postoperative analgesic remedies;Time of getting out of bed for the first time;The time of removing drainage tube after operation;Postoperative hospital stay;PCA pump press times;the first time after the operation to tolerate diet; Incidence of chronic pain after operation; | — |
Countries
China
Contacts
Public ContactZhang Mengyuan
Shandong Provincial Hospital
Outcome results
None listed