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A phase II study about the effect of Lixuesheng plant extract complex plus Bolten whey lactoferrin capsule on chemotherapy-induced myelosuppression

A phase II study about the effect of Lixuesheng plant extract complex plus Bolten whey lactoferrin capsule on chemotherapy-induced myelosuppression

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000039302
Enrollment
Unknown
Registered
2020-10-22
Start date
2020-11-02
Completion date
Unknown
Last updated
2021-01-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

Intervention group:chemotherapy combined with Lixuesheng plant extract complex plus Bolten whey lactoferrin capsule
Control group:Chemotherapy

Sponsors

National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with advanced lung cancer confirmed by clinic, pathology and / or cytology; 2. Patients aged 18-75 years; 3. Patients without myelosuppression symptoms within 3 months before treatment; 4. Patients receiving standard conventional chemotherapy; 5. Patients whose expected survival time is more than 3 months; 6. Patients with nrs2002 total score >= 3; 7. Patients with KPS score of 60 or above; 8. The subjects of gastrointestinal function evaluation meeting the enteral nutrition indications.

Exclusion criteria

Exclusion criteria: 1. Patients with severe organic diseases of cardiovascular, brain, lung, kidney and other important organs; 2. Patients with mental illness or inability to cooperate; 3. Patients with severe immune system diseases; 4. Patients with severe infection or other complications; 5. Subjects who are participating in clinical trials of other drugs.

Design outcomes

Primary

MeasureTime frame
Rate of myelosuppression =grade III;

Secondary

MeasureTime frame
Onset time of myelosuppression = grade III;NRS2002 score after chemotherapy;KPS score after chemotherapy;QLQ-C30 score after chemotherapy;Rate of G-CSF salvage application;Rate of IL-11/TPO salvage application;

Countries

China

Contacts

Public ContactXingsheng Hu

National Cancer Center / Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College

huxingsheng66@163.com+86 13641361385

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026