Breast Cancer
Conditions
Interventions
Lidocaine Group:Total intravenous anesthesia was used. Lidocaine was used in the induction and maintenance of anesthesia
Opioids Group:Total intravenous anesthesia was used. Opioids was used in the induction and maintenance of anesthesia
Sponsors
Tongji Hospital Affiliated to Tongji University
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Women who voluntarily participated in the study and whose age was >= 18 years old and <= 65 years old at the time of signing the informed consent; 2. Patients with primary breast cancer (T2-3, N0-2, M0); 3. Patients who plan to undergo unilateral radical mastectomy under general anesthesia; 4. American Society of anesthesiologists (ASA) grades I to III.
Exclusion criteria
Exclusion criteria: 1. Patients with inflammatory or metastatic breast cancer; 2. Patients who have received breast surgery; 3. Pregnant women; 4. Patients with severe diseases of heart, lung, liver, kidney and immune system 5. Patients with history of alcohol, sedatives or opioids addiction; 6. Patients allergic to lidocaine or any general anesthesia drugs; 7. Patients receiving preoperative radiotherapy or chemotherapy; 8. The patient can not cooperate with the study for any reason or other circumstances that the researcher thinks are not suitable for inclusion in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NLR;LMR;IL-6;IL-8;OFS;OS; | — |
Countries
China
Contacts
Public ContactLiu Jianhui
Tongji Hospital Affiliated to Tongji University
Outcome results
None listed