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Clinical observation of partial splenic artery embolization in the treatment of cirrhosis with hypersplenism under sequential regimen

Clinical observation of partial splenic artery embolization in the treatment of cirrhosis with hypersplenism under sequential regimen

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000039284
Enrollment
Unknown
Registered
2020-10-22
Start date
2020-11-01
Completion date
Unknown
Last updated
2021-01-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cirrhosis splenomegaly hypersplenism

Interventions

study group:sequential regimen
control group:One-time embolization

Sponsors

Changshu First People's Hospital, Changshu Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients with complete biochemical and imaging data to support the diagnosis of cirrhosis, splenomegaly and hypersplenism; 2. Patients aged 18-80 years, and no serious systemic diseases such as heart, lung, liver and kidney; 3. Subjects without any malignant tumor or hematological diseases.

Exclusion criteria

Exclusion criteria: 1. Those patients who take nonsteroidal anti-inflammatory drugs orally for a long time, antiplatelet drugs, anticoagulants and other drugs that may cause gastrointestinal bleeding; 2. Patients with upper gastrointestinal bleeding less than 3 times a year (excluding 3 times) or with different causes of bleeding; 3. Patients who do not agree to sign informed consent, do not comply with the requirements of this study, or fail to follow up on time or lose follow-up.

Design outcomes

Primary

MeasureTime frame
Hypersplenism improved;

Secondary

MeasureTime frame
Improvement of portal hypertension complications;Occurrence of adverse reactions;

Countries

China

Contacts

Public ContactXu Xiaodan

Changshu First People's Hospital, Changshu Affiliated Hospital of Soochow University

xxd20@163.com+86 18913631835

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026