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The safety and efficacy of propofol - midazolam - nabphine versus propofol - nabphine in elderly patients undergoing ERCP

The safety and efficacy of propofol - midazolam balanced sedation versus simple propofol sedation in elderly patients with ERCP

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000039265
Enrollment
Unknown
Registered
2020-10-22
Start date
2020-11-05
Completion date
Unknown
Last updated
2021-01-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ERCP Anesthesia in elderly patients

Interventions

Propofol group:Propofol - nabphine induced anesthesia, propofol target - controlled infusion to maintain anesthesia
Balanced propofol sedation:Propofol - midazolam - Nabphine induced anesthesia, propofol target controlled infusion to maintain anesthesia

Sponsors

The Second Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 89 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 65-89 years; 2. Patients with ASA II-III; 3. Patients scheduled for ERCP.

Exclusion criteria

Exclusion criteria: 1. Patients with BMI >= 28 kg / m2; 2. Patients with difficult airway; 3. Patients with uncontrolled hypertension had systolic blood pressure >= 180mmhg and diastolic blood pressure >= 110mmhg; 4. Patients allergic to narcotic drugs or their components; 5. Patients with previous history of mental illness and epilepsy; 6. Patients who refuse to sign informed consent.

Design outcomes

Primary

MeasureTime frame
Rate of use of Hyperensort;

Secondary

MeasureTime frame
the Incidence of hypertension;the incidence of hypoxemia;the incidence of bradycardia;the incidence of tachycardia;the incidence of malignant arrhythmias;the incidence of changing anesthesia methods;the incidence of death/sequelae due to sedation;recovery time;Operator satisfaction;patient satisfaction;

Countries

China

Contacts

Public ContactHuang Lining

Hebei Medical University

hlncctv@163.com+86 15803213730

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026