FFA inhibits BMSCs osteogenic differentiation through WNT/ -catenin signaling axis and affects bone healing in osteoporotic fractures of old age

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000039263

Enrollment

Unknown

Registered

2020-10-22

Start date

2021-01-01

Completion date

Unknown

Last updated

2021-01-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Clinical fractures

Interventions

elderly patients with osteoporotic hip fracture surgery:Nil

normal middle-aged and young patients with fracture surgery:Nil

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The fracture site samples collected from the elderly patients with osteoporotic hip fracture surgery and normal middle-aged and young patients with fracture surgery were divided into observation group and control group.

Exclusion criteria

Exclusion criteria: 1. Patients with multiple body injuries; 2. Patients with malignant tumor, liver insufficiency, renal insufficiency, metabolic abnormalities (excluding diabetes), severe edema and autoimmune diseases; 3. Patients without informed consent lose tissue samples; 4. Patients with pathological fracture.

Design outcomes

Primary

Measure	Time frame
Fatty acid;Osteogenesis index;	—

Countries

China

Contacts

Public ContactYin Ke

The First Affiliated Hospital of Nanhua University

357520637@qq.com+86 18973405240

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026