Acidosis
Conditions
Interventions
Sodium bicarbonate group:Infusion of sodium bicarbonate
Control group:Sodium bicarbonate was not infused
Sponsors
The First Affiliated Hospital of University of science and technology of China (Anhui Provincial Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients over 18 years old (including 18 years old); 2. Patients with major abdominal surgery.
Exclusion criteria
Exclusion criteria: 1. Patients over 80 years old (including 80 years old); 2. Patients with unplanned second operation; 3. Transplant patients; 4. Patients with respiratory failure and renal failure before operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mortality at 28 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| ICU admission rate after surgery;Length of hospital stay after surgery;Length of stay in ICU;Volume of intraoperative sodium bicarbonate infusion;Lac;PH;PaCO2;PaO2;Glu;Na+;K+;Ca2+;BE;HCO3-;Serum creatinine;Blood urea nitrogen;Sequential Organ Failure Assessment;Duration of mechanical ventilation;Is renal replacement therapy available?;Total amount of crystal liquid;Total amount of colloidal liquid;Total amount of bleeding;Total urine output; | — |
Countries
China
Contacts
Public ContactSheng Wang
The First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital)
Outcome results
None listed