Skip to content

Influence of preoperative sleep quality on early postoperative cognitive dysfunction and postoperative rapid recovery in elderly patients undergoing intra-spinal anesthesia

Influence of preoperative sleep quality on early postoperative cognitive dysfunction and postoperative rapid recovery in elderly patients undergoing intra-spinal anesthesia

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000039247
Enrollment
Unknown
Registered
2020-10-22
Start date
2020-11-01
Completion date
Unknown
Last updated
2021-01-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

unilateral total knee replacement

Interventions

high sleep quality group:Nil
low sleep quality group:Nil

Sponsors

Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: Spinal canal anesthesia downlink unilateral total knee replacement, aged 70-80, the American society of anesthesiologists (ASA) grade II - III level; The preoperative examination and test results were perfect and basically normal. No serious hypertension (grade 3), diabetes, coronary heart disease, hyperthyroidism, asthma and other systemic diseases

Exclusion criteria

Exclusion criteria: Absolute contraindications to spinal anesthesia; Allergic reaction to anesthetic drugs in the spinal canal; Previous history of severe hypertension (grade 3), diabetes, coronary heart disease, etc. Having a central nervous system disease or mental illness; A history of insomnia or mental illness; Patients with severe visual or hearing impairment, unable to cooperate with various scores; Preoperative Simple Mental State Assessment Scale (MMSE) score < 17 points.

Design outcomes

Primary

MeasureTime frame
mini-mental state examination;Interleukin-6;tumor necrosis factor-a;S100-ß;cortisol;

Secondary

MeasureTime frame
Sleep-wake rhythm;The 15-item recovery quality rating scale;

Countries

China

Contacts

Public ContactGuohai Xu

The Second Affiliated Hospital of Nanchang University

xuguohai@sina.com+86 13970008916

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026