Evaluating the Trends of Serum Fibrinogen in Chronic Periprosthetic Joint Infection Patients During the Perioperative Period

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000039244

Enrollment

Unknown

Registered

2020-10-22

Start date

2021-01-01

Completion date

Unknown

Last updated

2021-01-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periprosthetic Joint Infections

Interventions

chronic-PJI :N/A

primary joint replacement (PJR):N/A

ALP:N/A

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged over 18 (date of birth earlier than 1 January 2003). 2. Patients who have received total knee arthroplasty (TKA)/total hip arthroplasty (THA) before admission and have periprosthesis pain or dysfunction symptoms are considered to be admitted, chronic periprosthetic joint infection (PJI) and aseptic loosening of the prosthesis (ALP) are suspected by the first doctor in the clinic. 3. After professional evaluation and meeting the surgical indications, patients are proposed to undergo TKA/THA.

Exclusion criteria

Exclusion criteria: 1. Have a history of clotting disorder: malignant tumor, cerebrovascular disease, coronary disease, pulmonary embolism, etc. 2. History of autoimmune diseases: rheumatoid arthritis, mandatory spondylitis, systemic lupus erythematosus, inflammatory bowel disease, etc. 3. Unwilling to undergo surgery.

Design outcomes

Primary

Measure	Time frame
Fibrinogen;	—

Secondary

Measure	Time frame
C-reactive protein;Erythrocyte sedimentation rate;D-dimer;	—

Countries

China

Contacts

Public ContactBin Geng

Lanzhou University Second Hospital

cxxxf@foxmail.com+86 18394531090

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026