Stroke
Conditions
Interventions
Gold Standard:Computed tomography (CT), magnetic resonance imaging (MRI), ultrasound or angiography.
Index test:Electrochemiluminescence 
for 
serum 
PDGFRß 
and 
NfL 
protein 
in 
patients 
with 
stroke.
Sponsors
Shanghai Tongji Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Combined with clinical symptoms, signs and head MRI, it is clearly diagnosed as acute cerebral infarction (onset time <= 14 d). Acute cerebral infarction refers to the "Chinese Acute Ischemic Stroke Diagnosis and Treatment Guidelines 2018" formulated by the Neurology Branch of the Chinese Medical Association, and there is at least one cognitive area impairment). 2. First onset; 3. Aged 18 to 80 years; 4. No prodromal symptoms were seen before the onset, and cognitive function, motor function and social adaptability were all at a normal level; 5. Able to cooperate well with physical examination and neuropsychological assessment; 6. Those who voluntarily sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Various reasons (including language barrier, visual barrier, consciousness barrier, etc.) cannot complete the cognitive function evaluation. 2. A history of cognitive impairment; previous mental disorders such as anxiety, depression, and mental disorders, Hamilton Depression Rating Scale (HAMD) score >= 17 points. 4. Not cooperate with follow-up research. 5. Before the onset of the stroke, the mRS score was greater than 1. 6. Long-term drug abuse or drug dependence history.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PDGFRß;neurofilament light chain, NfL; | — |
Countries
China
Contacts
Public ContactQuan Wenqiang
Shanghai Tongji Hospital
Outcome results
None listed