Study on the depth of analgesia and sedation during tracheal intubation in ICU

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000039236

Enrollment

Unknown

Registered

2020-10-22

Start date

2020-11-30

Completion date

Unknown

Last updated

2021-01-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Critically ill children

Interventions

Group A:Midazolam (0.1mg/kg) + Esmamine (0.5mg/kg)

Group B: Midazolam (0.1mg/kg) + Esmamine (0.75mg/kg)

Group C:Midazolam (0.1mg/kg) + Sufentanil (0.3ug/kg)

Eligibility

Sex/Gender

All

Age

0.1 Years to 16 Years

Inclusion criteria

Inclusion criteria: Children who need tracheal intubation in ICU.

Exclusion criteria

Exclusion criteria: 1. The guardians of the subjects do not agree with the use of tracheal intubation or sedative drugs; 2. Allergic to the use of drugs; 3. Patients with severe liver and kidney damage; 4. Children with extremely unstable vital signs; 5. Patients with serious risk of blood pressure or intracranial pressure rise; patients with hypertension under control or without treatment; 6. Patients with hyperthyroidism without treatment or insufficient treatment. 7. In case of serious adverse reactions (such as cardiac arrest, respiratory arrest, severe allergic reactions, etc.), the study should be terminated immediately and active treatment measures should be taken.

Design outcomes

Primary

Measure	Time frame
Depth of sedation;	—

Countries

China

Contacts

Public ContactZhang Xinping

Hunan Children's Hospital

262190@qq.com+86 13787310806

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026