endometriosis-associated deep dyspareunia
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Subjects with persistent endometriosis-associated deep dyspareunia, with or without dysmenorrhea for more than 3 months.
Exclusion criteria
Exclusion criteria: 1.obstructive uropathy or symptomatic bowel stenosis; 2.evidence of complex adnexal cysts or an ovarian endometrioma of diameter more than 4 cm at vaginal ultrasonography; 3.therapies for endometriosis other than non-steroidal anti inflammatory drugs (NSAIDs) in the 3 months before study entry (6 months for GnRH analogues); 4.the typical contraindications to progestins; 5.the use of drugs that interfere with ovarian steroid metabolism; 6.allergy to components of the study medication; 7.abnormal findings at breast examination and mammary ultrasound scan; 8.an abnormal cervical smear; 9.a diagnosis of concomitant pelvic inflammatory disease, pelvic varices or genital malformations at previous surgery; 10.known gastrointestinal, urologic and orthopedic diseases; 11.psychiatric disturbances; 12.history of drug or alcohol abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pain evaluation;sexual functioning questionnaire; | — |
Countries
China
Contacts
Zhejiang Provincial People's Hospital