To compare the accuracy of 'drinking blush' and ALDH2 gene polymorphism in predicting myocardial injury in patients with limb ischemia-reperfusion

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000039173

Enrollment

Unknown

Registered

2020-10-21

Start date

2020-10-13

Completion date

Unknown

Last updated

2022-05-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ALDH2 gene and myocardial injury

Interventions

None listed

Eligibility

Sex/Gender

All

Age

65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. ASA grade II-V, cardiac function grade II-IV; 2. Age >65 years old, gender unlimited, BMI 18.5-30 kg/m2; 3. Orthopedic surgery is planned under tourniquet; 4. Voluntarily participate in this study and sign relevant informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with serious heart, lung, liver, kidney and cerebrovascular diseases; 2. Patients with severe trauma and unstable hemodynamics; 3. Patients with diseases of the blood system, such as anemia and coagulation disorder; 4. Patients with complicated mental system diseases who cannot cooperate with the research program; 5. Long-term use of hormone or immunosuppressant drugs before surgery; 6. History of substance dependence and drug abuse other than alcoho

Design outcomes

Primary

Measure	Time frame
ALDH2 genotypes;Troponin I;Postoperative cardiovascular complications;	—

Countries

China

Contacts

Public ContactZhengyi Han

The Second Affiliated Hospital of Anhui Medical University

983913245@qq.com+86 15155971268

Outcome results