Chronic periodontitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with informed consent; 2. Patients aged from 18 to 40 years old who are planning or undergoing orthodontic treatment; 3. Patients with at least one tooth position in the alveolar bone with two or three wall bone defect (i.e. angular absorption and vertical bone defect); 4. The patients with periodontal basic treatment had stable periodontal condition and good oral hygiene maintenance, which were identified as the cases with flap + bone graft indications by researchers, and the number of teeth requiring bone graft was no more than 3.
Exclusion criteria
Exclusion criteria: 1. Patients with uncontrollable pathological process in oral cavity; 2. Patients with known or suspected malignant tumor; 3. Patients with history of head and neck radiotherapy; 4. Patients with history of radiotherapy and chemotherapy within 5 years before operation; 5. Patients with uncontrollable diabetes mellitus; 6. Patients with steroid or other drugs that may affect postoperative healing; 7. Patients who smoke more than 10 cigarettes a day; 8. Those who drink and take drugs; 9. Patients who participate in other clinical studies at the same time or in other clinical studies a few weeks before employment; 10. Pregnant women or women with pregnancy plans during the study period; 11. Patients who do not have clinical bone graft conditions; 12. Patients with severe periodontitis or patients with more than 3 teeth in bone graft area; 13. The situations that the researchers think are not suitable to participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the augmentation of alveolar bone hight; | — |
Secondary
| Measure | Time frame |
|---|---|
| speed of tooth movement;clinical attachment level;probing depth; | — |
Countries
China
Contacts
Shanghai Stomatological Hospital