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The effect of external force on periodontal tissue remodeling after alveolar bone augmentation surgery

The effect of external force on periodontal tissue remodeling after alveolar bone augmentation surgery

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000039150
Enrollment
Unknown
Registered
2020-10-20
Start date
2021-01-01
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic periodontitis

Interventions

1:orthodontic force 2w after surgery
2:orthodontic force 12w after surgery

Sponsors

Shanghai Stomatological Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Patients with informed consent; 2. Patients aged from 18 to 40 years old who are planning or undergoing orthodontic treatment; 3. Patients with at least one tooth position in the alveolar bone with two or three wall bone defect (i.e. angular absorption and vertical bone defect); 4. The patients with periodontal basic treatment had stable periodontal condition and good oral hygiene maintenance, which were identified as the cases with flap + bone graft indications by researchers, and the number of teeth requiring bone graft was no more than 3.

Exclusion criteria

Exclusion criteria: 1. Patients with uncontrollable pathological process in oral cavity; 2. Patients with known or suspected malignant tumor; 3. Patients with history of head and neck radiotherapy; 4. Patients with history of radiotherapy and chemotherapy within 5 years before operation; 5. Patients with uncontrollable diabetes mellitus; 6. Patients with steroid or other drugs that may affect postoperative healing; 7. Patients who smoke more than 10 cigarettes a day; 8. Those who drink and take drugs; 9. Patients who participate in other clinical studies at the same time or in other clinical studies a few weeks before employment; 10. Pregnant women or women with pregnancy plans during the study period; 11. Patients who do not have clinical bone graft conditions; 12. Patients with severe periodontitis or patients with more than 3 teeth in bone graft area; 13. The situations that the researchers think are not suitable to participate in this clinical trial.

Design outcomes

Primary

MeasureTime frame
the augmentation of alveolar bone hight;

Secondary

MeasureTime frame
speed of tooth movement;clinical attachment level;probing depth;

Countries

China

Contacts

Public ContactMeihua Chen

Shanghai Stomatological Hospital

cathychendt@163.com+86 13764241540

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026