Postoperative atelectasis
Conditions
Interventions
Optimal Cstat titrating iPEEP:Use optimal static lung compliance directed individualized PEEP titration to choose the ideal PEEP for each patient.And ventilate patients intraoperatively with the idea
EIT titrating iPEEP:Use electrical impedance tomography guided individualized PEEP titration to choose the ideal PEEP for each patient.And ventilate patients intraoperatively with the ideal PEEP.
Sponsors
Beijing Friendship Hospital affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients with BMI > 32.5; 2. Patients scheduled for weight loss and metabolic surgery under general anesthesia and laparoscopy; 3. Patients aged 18-60 years old; 4. Patients with moderate or high risk of postoperative pulmonary complications; 5. ASA I-III patients; 6. Patients who signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients aged 60; 2. Patients with ASA grade > or = IV; 3. Patients with severe chronic obstructive pulmonary disease (COPD, gold grade III-IV); 4. Patients with a history of severe or uncontrollable bronchial asthma; 5. Patients with pulmonary metastases; 6. Patients undergoing renal replacement therapy before surgery; 7. Patients with congestive heart failure (NYHA grade III-IV); 8. Patients who can't extubate in time after operation and need to take the tube back to ICU.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| percent mass of collapsed lung tissue; | — |
Secondary
| Measure | Time frame |
|---|---|
| the ratio of arterial oxygenation partial pressure to inspiratory oxygen fractionto;ventilation parameters;postoperative pulmonary complications;health economics indicators;hemodynamic parameter;blood gas parameters;anesthesia medicine dosage;recovery time of anesthesia;PCT;IL-6; | — |
Countries
China
Contacts
Public ContactLixin An
Beijing Friendship Hospital Affiliated to Capital Medical University
Outcome results
None listed