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Diagnostic value of mNGS in etiology in patients with sepsis

Diagnostic value of mNGS in etiology in patients with sepsis

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000039108
Enrollment
Unknown
Registered
2020-10-17
Start date
2020-11-01
Completion date
Unknown
Last updated
2021-01-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

Gold Standard:Traditional pathogen culture

Sponsors

The First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged from 14 to 80 years old, regardless of gender; 2. All the selected patients were patients with sepsis or septic shock. The infection index of laboratory examination was increased, with or without imaging examination of infection basis or with hemodynamic instability; 3. For the patients who must sign the informed consent form before the start of all specific research procedures, the informed consent form shall be signed by the patient or the authorized client for the patients who are 18 years old or above; the informed consent form shall be signed by the legal guardian for the patients who are under 18 years old, and the informed consent form shall also be signed by the subjects themselves. Considering the patient's condition, if the patient's signature is not conducive to the treatment of the disease, the legal guardian or the patient's immediate family members should sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with incomplete medical history; 2. Lost patients; 3. Patients whose etiology has been confirmed before admission; 4. Patients allergic to anti infective drugs; 5. The patient or authorized client refuses to perform mngs test.

Design outcomes

Primary

MeasureTime frame
Infection index;SEN, SPE, ACC, AUC of ROC, PPV, NPV;

Countries

China

Contacts

Public ContactZheng Changcheng

The First Affiliated Hospital of University of science and technology of China (Anhui Provincial Hospital)

zhengchch1123@163.com+86 13956961162

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026