Lumbar Disc Herniation
Conditions
Interventions
Control Group:Endoscopic surgery
Sponsors
The Ninth People's Hospital Affiliated to Medical College of Shanghai Jiaotong University
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Young and middle-aged patients aged 20-60 years old; 2. Patients with severe lumbocrural pain, recurrent attacks, ineffective after more than 3 months of non-surgical treatment, affecting work or life; 3. For patients with herniation of nucleus pulposus, L3-L4, L4-L5 and L5-S1 were the single responsible segments, and the imaging evidence was consistent with clinical symptoms and signs; 4. Patients with Pfirrmann grade II-IV judged by MRI T2 weighted images; 5. Patients who need endoscopic surgery conditions; 6. Patients who voluntarily participate in the trial are willing to sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with vertebral segment instability such as spondylolisthesis requiring fusion; 2. Patients with unexplained back pain or non root leg pain; 3. Patients with lumbosacral cone damage caused by tumor, trauma, tuberculosis and various infectious and metabolic diseases; 4. Patients with poor general condition and severe impairment of heart, lung, brain, kidney and other important organs and hematopoietic function; 5. Patients with systemic or local active infection; 6. Patients with mental and neurological disorders who cannot cooperate with treatment; 7. Patients who have recently received radiotherapy, chemotherapy, immunosuppressant and anticoagulant therapy; 8. Patients with allergic constitution or allergic to materials and reagents related to disease treatment; 9. Pregnant and lactating women; 10. Patients who participated in other clinical trials in recent 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ODI score;Incidence of symptomatic reherniation;Complications;Surgical data; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS score;Pfirrmann grade; | — |
Countries
China
Contacts
Public ContactYouzhuan Xie
The Ninth People's Hospital Affiliated to Medical College of Shanghai Jiaotong University
Outcome results
None listed