Tumors
Conditions
Interventions
Gold Standard:Pathologic diagnosis
Index test:1. 
CT 
imaging 
tumor 
activating 
protein 
(FAP)
2. 
Sponsors
Department of Nuclear Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients aged 18-80 years old, male or female; 2. Subjects with solid tumors or suspected tumors who plan to undergo pathological biopsy or tumor surgery in the near future (within 2 months); 3. Patients with expected survival >= 12 weeks; 4. Patients whose blood routine and liver and kidney function meet the following criteria: blood routine: WBC >= 4.0 x 10^9/L or neutrophil >= 1.5 x 10^9/L, PLT >= 100 x 10^9 /L, Hb >= 90g /L; PT or APTT <= 1.5 ULN; liver and kidney function: T-Bil <= 1.5 x ULT (upper limit of normal value), ALT / AST <= 2.5 ULN or <= 5 x ULT (liver metastasis subjects), ALP <= 2.5 ULN(if there is bone metastasis or liver metastasis, ALP <= 4.5uln), bun <= 1.5 x ULT, SCR <= 1.5 x ULT; 5. Patients with at least one measurable target lesion according to recist1.1; 6. Patients who understand and sign informed consent voluntarily.
Exclusion criteria
Exclusion criteria: 1. Patients with severe abnormal liver and kidney function; 2. Pregnant, pregnant and lactating women; 3. Patients who cannot lie on their back for half an hour; 4. Patients with claustrophobia or other mental diseases; 5. Other researchers think that it is not suitable to participate in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SUVmax;SEN, SPE, ACC, AUC of ROC, PPV, NPV; | — |
Countries
China
Contacts
Public ContactXiaohua Zhu
Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology
Outcome results
None listed