Repeated implantation failure
Conditions
Sponsors
Fujian Maternity and Child Health Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Patients who meet the diagnostic criteria of Western medicine and traditional Chinese medicine; 2. Patients who have obtained excellent embryos of grade 1-2 after oocyte retrieval; 3. Patients aged 20-40 years; 4. Patients have independent ability, agree to accept the treatment plan of this study, obey the research arrangement, and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients under 20 years old or over 40 years old; 2. Patients with organic diseases or other endocrine diseases were excluded: female genital malformations, including uterine malformations (single horn uterus, double horn uterus, mediastinal uterus and double uterus), adenomyosis, submucosal myoma and intrauterine adhesions, hyperprolactinemia, abnormal thyroid function and other reproductive endocrine diseases and autoimmune diseases; 3. Patients with primary diseases such as liver and kidney, cerebrovascular, cardiovascular and hematopoietic disorders, and psychosis; 4. Patients allergic to aspirin or other salicylates or other components of drugs; 5. Patients with history of gastric or duodenal ulcer or gastrointestinal bleeding or other cases of aspirin forbidden; 6. Data were incomplete.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TCM symptom score;pregnancy outcome;Coagulation related indicators;JAK, stat and other gene transcription levels;Expression and phosphorylation of JAK and stat related proteins; | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety inspection index; | — |
Countries
China
Contacts
Public ContactYou Xiumi
Fujian Maternity and Child Health Hospital
Outcome results
None listed