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Study on the relationship between vaginal flora and endometriosis development

Study on the relationship between vaginal flora and endometriosis development

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000039078
Enrollment
Unknown
Registered
2020-10-16
Start date
2020-10-20
Completion date
Unknown
Last updated
2021-01-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis

Interventions

endometriosis group:Nil
healthy control group:Nil

Sponsors

The Second Affiliated Hospital of Nanchang University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Subjects aged 18-55 years; regular menstrual cycle (28 ± 7 days); 2. Patients confirmed by imaging; 3. No asexual life, no vaginal flushing and vaginal medication within 2 days; no cervical treatment within 7 days; no antibiotic drugs within 30 days; 4. There is no abnormal object in vaginal secretion examination; the white blood cell count and neutrophil ratio in blood routine test are within the normal range.

Exclusion criteria

Exclusion criteria: 1. The subjects with drug treatment history within 3 months before treatment (oral contraceptives, progesterone and other drugs for the treatment of endometriosis and drugs for other diseases, excluding GnRHa for the treatment of this disease), and probiotics (including health care products); 2. Patients with IUD insertion; 3. Subjects of pregnancy and lactation; 4. Patients with other diseases, such as vaginal cancer or surgical history, acute or severe vaginal symptoms requiring treatment, vaginal infection or onset. Combined with autoimmune diseases, systemic acute inflammation, genital tract malformations.

Design outcomes

Primary

MeasureTime frame
High throughput sequencing of vaginal secretion;

Countries

China

Contacts

Public ContactTan Buzhen

The Second Affiliated Hospital of Nanchang University

1300513524@qq.com+86 13979191592

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026