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Imaging analysis and health related quality of life study of paraspinal muscle degeneration in patient with degenerative lumbar scoliosis

Imaging analysis and health related quality of life study of paraspinal muscle degeneration in patient with degenerative lumbar scoliosis

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000039073
Enrollment
Unknown
Registered
2020-10-15
Start date
2020-11-01
Completion date
Unknown
Last updated
2021-01-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Degenerative lumbar scoliosis

Interventions

DLS:Nil
LSS:Nil

Sponsors

The Third Hospital of Peking University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Healthy people: (1) Aged >= 20 years; (2) Except for chronic low back and leg pain, previous spinal deformity, spinal surgery, pelvic, hip and lower limb diseases; (3) There was no spondylolisthesis in the whole spine on the anteroposterior and lateral X-ray images, and no sagittal kyphosis was found when the Cobb angle of coronal scoliosis was less than 5 degrees. (4) They agreed to participate in the study and signed the informed consent. 2. DLS case group: Inclusion criteria: Patients with clinically diagnosed degenerative lumbar scoliosis (DLS), over 40 years old, with complete clinical information and imaging data, who were examined or operated in our hospital. 3. Control group A (patients with common lumbar spinal stenosis) No scoliosis, kyphosis, coronal or sagittal imbalance of the spine, and complete clinical information were found.

Exclusion criteria

Exclusion criteria: 1. Healthy people: (1) Patients with spinal deformity; (2) The patients who could not cooperate with CT and MRI scan and take the whole spine anteroposterior and lateral X-ray; (3) Patients with metal implants in the body; (4) Pregnant women or those with pregnancy planning in the near future; (5) Refused to participate in the study 2. DLS group: idiopathic scoliosis, neuromuscular scoliosis, non structural scoliosis, spinal tumor, spinal tuberculosis, ankylosing spondylitis, humen's disease, spinal surgery history, spinal trauma history and hip surgery history. 3. Control group A (patients with common lumbar spinal stenosis): idiopathic scoliosis, neuromuscular scoliosis, non structural scoliosis, spinal tumor, spinal tuberculosis, ankylosing spondylitis, humen's disease, spinal surgery history, spinal trauma history and hip surgery history.

Design outcomes

Primary

MeasureTime frame
Paravertebral muscle area and degree of fat infiltration;

Countries

China

Contacts

Public ContactYan Zeng

The Third Hospital of Peking University

zyanby73@163.com+86 18518590006

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 6, 2026