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Diagnostic value of mNGS in patients with neutropenia and fever

Diagnostic value of mNGS in patients with neutropenia and fever

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000039026
Enrollment
Unknown
Registered
2020-10-13
Start date
2020-11-01
Completion date
Unknown
Last updated
2021-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neutropenia with fever

Interventions

Sponsors

The First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged from 14 to 80 years, including men and women; 2. All the selected patients are patients with hematological diseases with neutropenia, elevated body temperature, elevated laboratory infection indicators, and evidence of infection with or without imaging tests; 3. The informed consent form must be signed before the start of all the specific research procedures. Patients aged 18 and above must sign the informed consent form by the patient or an authorized consignor; adolescent patients under the age of 18 must sign the informed consent form with the consent of their legal guardian, and take the test at the same time The person himself also needs to sign an informed consent form. Considering the patient's condition, if the patient's signature is not conducive to the treatment of the condition, the legal guardian or the patient's immediate family members will sign the informed consent.

Exclusion criteria

Exclusion criteria: 1) Incomplete medical history data; 2) Those who are lost to follow-up; 3) The final diagnosis is a non-infectious fever patient; 4) Those whose etiology has been clarified before admission; 5) Those who are allergic to anti-infective drugs; 6) The patient himself or the authorized client refuses to perform mNGS testing.

Design outcomes

Primary

MeasureTime frame
Infection index;SEN, SPE, ACC, AUC of ROC, PPV, NPV;

Countries

China

Contacts

Public ContactZhengchangcheng

The First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital)

zhengchch1123@163.com+86 13956961162

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026