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Effects of inhalation and intravenous anesthetics on perioperative CD8+T cell function in patients with colorectal cancer

Effects of inhalation and intravenous anesthetics on perioperative CD8+T cell function in patients with colorectal cancer

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000039025
Enrollment
Unknown
Registered
2020-10-13
Start date
2020-10-20
Completion date
Unknown
Last updated
2021-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal cancer

Interventions

Inhalation anesthesia group:Intravenous anesthesia
Intravenous anesthesia group:Intravenous anesthesia

Sponsors

The Affiliated Hospital of Southwest Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 18-80 years with elective colorectal cancer surgery; 2. The body mass index is between 18.5 and 24; 3. ASA I-III; 4. Duration of general anesthesia is more than 2 hours.

Exclusion criteria

Exclusion criteria: 1. A history of substance abuse; 2. Diseases related to the immune system; 3. Emergency surgery; 4. Perioperative blood transfusion; 5. Pregnancy; 6. The patient refuses.

Design outcomes

Primary

MeasureTime frame
Programmed cell death protein 1;CD28;CD8;—

Secondary

MeasureTime frame
CD3;CD4;The transcription factor Forkhead Box P3;CD45RO;CD62L;TNF-a;IFN-?;—

Countries

China

Contacts

Public ContactYiping Bai

The Affiliated Hospital of Southwest Medical University

baiyiping0608@163.com+86 18982797213

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026