Clinical study of iodine-125 seeds in the treatment of intracranial metastases

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000039024

Enrollment

Unknown

Registered

2020-10-13

Start date

2020-10-15

Completion date

Unknown

Last updated

2021-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intracranial metastases

Interventions

experimental group:I-125 particle therapy

Control group-1 :Gamma knife therapy-1

Control group-2 :Whole brain radiotherapy

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients with brain metastases refused craniotomy. Tumor diameter = 6 months, KPS (Karnofsky performance score) score >= 60.

Exclusion criteria

Exclusion criteria: Brain stem metastasis.

Design outcomes

Primary

Measure	Time frame
Tumor size;survival time;Karnofsky performance score;Carcinoembryonic antigen;	—

Countries

China

Contacts

Public ContactZhang Hong-Wei

The Second Hopipital of Tianjin Medical University

zhhwmen@163.com+86 13820207469

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026