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Comparison of dexmedetomidine and propofol in the treatment of pediatric Emergence agitation: a randomized controlled trial

Comparison of dexmedetomidine and propofol in the treatment of pediatric Emergence agitation: a randomized controlled trial

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000039021
Enrollment
Unknown
Registered
2020-10-13
Start date
2020-10-01
Completion date
Unknown
Last updated
2021-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Emergence agitation

Interventions

Group P:Propofol, intravenous injection (1-2mg/kg)
Group D:Dexmedetomidine, intravenous injection (0.5-1ug/kg)

Sponsors

Children's Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 14 Years

Inclusion criteria

Inclusion criteria: 1. Children who undergo elective surgery and have agitation during the resuscitation period; 2. American Society of Anesthesiologists (ASA) score I or II; 3. Aged 1-14 years, male or female; 4. Sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. History of upper respiratory tract infection within 2 weeks before surgery; 2. A history of heart disease and mental illness; 3. A history of allergy to dexmedetomidine, propofol or other narcotic drugs; 4. A history of neurological and neuromuscular diseases; 5. Liver and kidney dysfunction; 6. Maxillofacial deformity or abnormal development.

Design outcomes

Primary

MeasureTime frame
Pediatric Anesthesia Emergence Delirium (PAED);

Secondary

MeasureTime frame
Time in the resuscitation room;

Countries

China

Contacts

Public ContactXuemin Han

Children's Hospital of Soochow University

1984253489@qq.com+86 18550083856

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026