Fentanyl-induced cough
Conditions
Interventions
Intervention group 1:nalmefene 0.05ug/kg
Intervention group 2:nalmefene 0.1ug/kg
intervention group 3:nalmefene 0.2ug/kg
Sponsors
The Children's Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
2 Years to 10 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 2-10 years, the body weight is ± 15% of the ideal body weight, regardless of gender; 2. Patients with ASA grade I - II, the estimated operation time was less than 90 min; 3. Children undergoing laparoscopic hernia repair under selective general anesthesia; 4. Patients whose guardians clearly understand, voluntarily participate in the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with a history of hearing impairment or visual impairment; 2. Patients with history of bronchial asthma and respiratory tract infection in recent 4 weeks; 3. Patients with tongue and mouth deformity and history of allergy to any narcotic drugs; 4. Patients with congenital heart disease or severe heart, lung, liver and kidney dysfunction, and patients taking psychotropic drugs; 5. Patients who can't cooperate with serious crying.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence and extent of fentanyl induced cough; | — |
Secondary
| Measure | Time frame |
|---|---|
| Wong-Baker pain rating scale;NIBP;HR;SpO2;Face, Legs, Activity, Cry and Consolability scores; | — |
Countries
China
Contacts
Public ContactXia Chen
Children's Hospital Affiliated to Suzhou University
Outcome results
None listed